Secular trends in the initiation of therapy in secondary fracture prevention in Europe: a multi-national cohort study including data from Denmark, Catalonia, and the United Kingdom.

Osteoporos Int · 2020 · PMC7360649 · PMID 32185437

Europe PMC DOI

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a decreasing trendno p-value reported

In comparison, the treatment gap was lowest in the UK at the starting point in 2005–07 and demonstrated a decreasing trend during the two subsequent time periods.

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an increasing trendno p-value reported

The treatment gap among patients with spine fractures demonstrated an increasing trend towards the end of this study.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.