As discussed, the small sample size was a weakness of the study because the findings of borderline significance could represent a true difference.
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Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis.
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In this study, stromal MMP-14 showed borderline significance, so a larger number of patients could have shown that MMP-14, along with MMP-2 and TIMP-2 in the stroma, was significantly associated with lower survival.