The single-locus survival signature for TAM is also significantly enriched at the 7-month time point in the T47D RA experiment ( p = 0.0032), but not for ER+/HER2- despite an increasing trend in the proportion of CpGs contributing to enrichment in the same direction (‘up’) over time (Table 4 ).
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Candidate methylation sites associated with endocrine therapy resistance in ER+/HER2- breast cancer.
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