Barely Significant
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Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs).

PLoS Negl Trop Dis · 2020 · PMC7373315 · PMID 32644998

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highly significantno p-value reported
By contrast, LPS stimulation elicited a highly significant increase in levels of IL-6 and TNF secreted by THP-1 macrophages.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.