Adjuvant regional nodal irradiation did not improve outcomes in T1-2N1 breast cancer after breast-conserving surgery: A propensity score matching analysis of BIG02/98 and BCIRG005 trials.

In addition, these two trials are lack of quality control for radiation therapy, thus the characteristics of the radiotherapy used in each study, such as fractionation size, treatment volumes and fields, total dose, and tumor bed boost or no boost, might be significant different, which makes it more complicated to establish comparative similarities between the patients of both studies.

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