Transcutaneous Auricular Vagus Nerve Stimulation at 20 Hz Improves Depression-Like Behaviors and Down-Regulates the Hyperactivity of HPA Axis in Chronic Unpredictable Mild Stress Model Rats.

Front Neurosci · 2020 · PMC7378324 · PMID 32765210

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a decreasing trendno p-value reported

A decreasing trend of the mean concentration of plasma CORT was observed in the CUMS group and different frequencies taVNS groups exposed to CUMS, but a significant difference was only found between the 20-Hz group and the CUMS group ( P < 0.01) ( Figure 3A ).

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