The relationship of the immune response mediator genes’ polymorphic variants with the methotrexate efficacy in juvenile idiopathic arthritis

Turk J Med Sci · 2020 · PMC7379423 · PMID 31958219

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borderline significanceno p-value reported

When studying the PADI4 rs2240336 polymorphic locus, a borderline significance level tendency was observed for the increase of the proportion of the PADI4 rs2240336*GA genotype and the decrease of the proportion of the PADI4 rs2240336*GG genotype in JIA patients with the absence of the response to methotrexate (*GA: pcor = 0.053 and *GG: pcor = 0.053, respectively).

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