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Accurate Prediction of Coronary Heart Disease for Patients With Hypertension From Electronic Health Records With Big Data and Machine-Learning Methods: Model Development and Performance Evaluation.

JMIR Med Inform · 2020 · PMC7381262 · PMID 32628616

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an increasing trendno p-value reported
Moreover, variables indicating an increasing trend of medical activities (eg, in-hospital or out-hospital records but without a CHD-related diagnosis or medical examinations) were shown to be correlated with a future risk of CHD onset, which warrants further investigations.

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