Comparing the quartets with 2 archaea and 2 bacteria to the remaining quartets using the Wilcoxon rank-sum test revealed that the difference between the two sets is extremely significant (Z-score greater than 1000).
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A New Phylogenomic Approach For Quantifying Horizontal Gene Transfer Trends in Prokaryotes.
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The sentences
Statistical computations show that these differences in HGT frequency are highly significant.