MicroRNA-654-3p enhances cisplatin sensitivity by targeting QPRT and inhibiting the PI3K/AKT signaling pathway in ovarian cancer cells.

Exp Ther Med · 2020 · PMC7388328 · PMID 32742380

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may be significantno p-value reported

The results of the present study demonstrated that overexpression of miR-654-3p could inhibit the activation of PI3K/AKT pathways, and targeting the miR-654-3p/QPRT/PI3K/AKT axis may be significant to overcome the problem of DDP resistance.

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