Identification of protective peptides of Fasciola hepatica-derived cathepsin L1 (FhCL1) in vaccinated sheep by a linear B-cell epitope mapping approach.

In contrast to what was observed in sheep from G1 with respect to peptide 102, an increasing trend in binding was detected after the experimental challenge (Fig. 3 ).

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When comparing peptide recognition between the different time points, the highest binding was found for peptides 52–53 and 102 after vaccination and before infection, though a decreasing trend in reactivity was observed from that time point onwards.

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