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Parathyroid hormone (1-34) promotes the effects of 3D printed scaffold-seeded bone marrow mesenchymal stem cells on meniscus regeneration.

Stem Cell Res Ther · 2020 · PMC7394673 · PMID 32731897

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In this study, 3D printed scaffolds were seeded with canine BMSCs and cultured under chondrogenic culture medium in vitro, and the BMSCs–scaffold showed an increasing trend of cell proliferation and ECM, GAG, and Col2 synthesis, which reached the highest levels on day 21 of culture, and declined on day 28; the decline may be related to hypertrophy of BMSCs during long-term chondrogenic induction in vitro.

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