Barely Significant
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The Pharmacokinetic and Pharmacodynamic Properties of Hydroxychloroquine and Dose Selection for COVID-19: Putting the Cart Before the Horse.

Infect Dis Ther · 2020 · PMC7395206 · PMID 32740858

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likely to be significantno p-value reported
Furthermore, if a target is identified, there is likely to be significant variation in PK in patients infected with COVID-19 that is not properly accounted for in the simulation studies published.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.