Barely Significant
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43-Year Temporal Trends in Immune Response to Oral Bacteria in a Swedish Population.

Pathogens · 2020 · PMC7400255 · PMID 32645865

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a decreasing trendno p-value reported
brevis (50-year-olds), and a decreasing trend for S. intermedius (30-year-olds).

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borderline significantno p-value reported
When stratifying the analyses by age, both age groups had significantly (or borderline significant) increased antibody responses over time for A. viscosus, B. dentium, B. longum , C. durum, C. matruchotii, F. alocis, H. parainfluenzae, S. cristatus, and S. mutans , and decreasing responses to S. oralis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.