It varies with region and is an increasing trend. 4 In the studies reviewed in children within the last 5 years, we observed that in most of them the resistance rates to CLA and MET exceed 20%, with CLA resistance prevailing and with very little resistance to amoxicillin (AMO) and levofloxacin. 27–29 Multidrug resistance was a problem. 27 28 30 R
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