Prefusion RSV F Immunization Elicits Th2-Mediated Lung Pathology in Mice When Formulated With a Th2 (but Not a Th1/Th2-Balanced) Adjuvant Despite Complete Viral Protection.

Front Immunol · 2020 · PMC7403488 · PMID 32849580

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did not achieve significanceno p-value reported

Moreover, PreF/Alum-immunized mice had increased IL5+ ( Figure 4E ) and IL-13+ ( Figure 4F ) ILC2 populations as compared to PreF/Advax-SM-immunized mice and PBS controls; once again, increased trends in the PreF alone group did not achieve significance.

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