Anti-Inflammatory and Chemopreventive Effects of <i>Bryophyllum pinnatum</i> (Lamarck) Leaf Extract in Experimental Colitis Models in Rodents.

An increasing trend was observed in the expression of ZO-1, occluding, and MUC-2 ( p ≥ 0.05 vs DNBS group) and MUC-3 expression was significantly increased (p < 0.05 vs DNBS group) by HEBP administration at the 100 mg/kg dose.

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No significant differences ( p ≥ 0.05) were observed in the weight/length ratio ( Figure 6E ) of the colon when compared to the DSS group once the mice were sacrificed, although a decreasing trend was observed with the higher assayed dose.

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