Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres.

Gene Ontology (GO) analysis confirmed that antiviral responses were the most enriched categories in the upregulated genes ( Figure 3 E), and gene set enrichment analysis (GSEA) uncovered that upregulation of IFN response signatures was highly significant in TLK-depleted cells ( Figure 3 F).

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