Mapping of Recognition Sites of Monoclonal Antibodies Responsible for the Inhibition of Pneumolysin Functional Activity.

Biomolecules · 2020 · PMC7408604 · PMID 32650398

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highly significantno p-value reported

The tyrosine Y461 (changed to serine (S563) in SLO), glutamine Q463 (changed to tyrosine (Y565) in SLO) and glutamic acid E465 (changed to serine (S567) in SLO) were also suggested as highly significant for the interaction of the MAb 6E5 with VLY, ILY, LLO, PFO, INY.

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