Decreased Riboflavin Impregnation Time Does Not Increase the Risk for Endothelial Phototoxicity During Corneal Cross-Linking.

UVA alone, RF alone, and the combination of RF and consecutive UVA irradiation show a highly significant trend toward reduced cell viability (all P < 0.001). β-Coefficients for UVA irradiation, RF concentration, and their interaction term are −29.3% per mW/cm 2 UVA, −605.2% per % RF, and −1206.9% per mW/cm 2 UVA * % RF, respectively.

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