Barely Significant
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<i>SOX1</i> Promoter Hypermethylation as a Potential Biomarker for High-Grade Squamous Intraepithelial Neoplasia Lesion and Cervical Carcinoma: A Meta-Analysis With Trial Sequential Analysis.

Front Genet · 2020 · PMC7411256 · PMID 32849763

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The sentences

an increasing trendp < 0.001actually significant
As shown in Table 2 , the pooled rates of SOX1 hypermethylation showed an increasing trend ( p < 0.001) from the LSIL specimens (27.27%, 95% CI: 4.43%−20.81%) to the HSIL specimens (40.75%, 95% CI: 24.27%−63.27%) and ultimately to the CC specimens (84.56%, 95% CI: 83.59%−93.08%).

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