In addition, TUNEL staining also exhibited an increasing trend of cardiomyocyte apoptosis in the db/db model ( Fig. 1F ), suggesting successful establishment of a model of early-stage DCM. circRNA expression in the myocardial tissue of db/db mice To detect circRNA expression in the myocardial tissues of db/db mice, RNA-seq analysis was performed.
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Expression profiling of circular RNAs and their potential role in early‑stage diabetic cardiomyopathy.
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