Optimization Extraction of Shikonin Using Ultrasound-Assisted Response Surface Methodology and Antibacterial Studies.

Evid Based Complement Alternat Med · 2020 · PMC7411493 · PMID 32802111

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an increasing trendno p-value reported

After incubation for 3 h, the growth rate in the shikonin group was always lower than that of the blank control group; after treatment with the 1/2× MIC, an increasing trend was observed, but compared with that in the blank group, the growth of bacteria in the shikonin group was only mildly inhibited.

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