An In Vitro Bovine Cellular Model for Human Schlemm's Canal Endothelial Cells and Their Response to TGFβ Treatment.

Transl Vis Sci Technol · 2020 · PMC7414733 · PMID 32832237

Europe PMC DOI

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highly significantP = 2.33 × 10 – 6actually significant

40 Because the association of TGFβ as an upstream regulator was highly significant ( P = 2.33 × 10 – 6 ) and all differentially expressed genes were engaged in the TGFβ pathway, we decided to further study the role of TGFβ on these mechanoresponsive glaucoma-related genes in bovine AAP cells first, followed by validation in human SC cells.

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