Epigenetics meets GPCR: inhibition of histone H3 methyltransferase (G9a) and histamine H<sub>3</sub> receptor for Prader-Willi Syndrome.

Sci Rep · 2020 · PMC7419559 · PMID 32782417

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highly significantno p-value reported

Though highly significant clinical studies for pitolisant in PWS patients are missing to date, recent patient-based case reports suggest benefits of this H 3 R targeting drug.

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