Despite the levels of overexpressed RCC1L V3 being lower than RCC1L V1 , we were able to detect a decreasing trend in mtSSU protein mS29, MT-CO1 and MT-CO2 along with an increase in mtLSU component uL11 but no change in OxPhos proteins ATP5A and UQCRC2 ( Fig 2A and 2B ).
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RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases.
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