Circular RNA hsa_circ_0076690 acts as a prognostic biomarker in osteoporosis and regulates osteogenic differentiation of hBMSCs via sponging miR-152.

Aging (Albany NY) · 2020 · PMC7425508 · PMID 32717724

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an increasing trendno p-value reported

Our dual-luciferase reporter assay revealed that miR-152 directly targeted RUNX2 in hBMSC cells and its expression was gradually decreased in a time-dependent manner during osteogenic differentiation of hBMSCs, while hsa_circ_0076690 showed an increasing trend.

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