Effects of Levetiracetam Compared to Valproate on Cognitive Functions of Patients with Epilepsy.

18 , 19 In the current study, it was found that there were highly significant improvements in attention and concentration measured by the WCST in the LEV group, in agreement with Noh et al, who found improvement in domains of cognition in patients treated with LEV as monotherapy. 20 Furthermore, that a highly significant improvements in processing speed, mental flexibility, and executive functioning on trail-making tests A and B in the LEV group compared to the VPA group were demonstrated, in agreement with previous studies 21 , 22 finding that both trail-making test A and reaction-time results showed significant differences with LEV treatment.

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