Age-Related Memory Impairment Is Associated with Increased zif268 Protein Accumulation and Decreased Rpt6 Phosphorylation.

Int J Mol Sci · 2020 · PMC7432048 · PMID 32731408

Europe PMC DOI

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closest p · 1.2× alpha

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boldest claim

The sentences

marginally significantp = 0.06so close (0.05 < p ≤ 0.1)

A 3 (Group: 3 mo, 15 mo, 22 mo) × Time Period (CS, ITI, Post-CS) ANOVA conducted to assess responding during this session found a main effect of time period, F (2, 34) = 6.46, MSE = 1067.50, p = 0.004, η p 2 = 0.28, a marginally significant interaction, F (3, 34) = 2.57, MSE = 1067.50, p = 0.06, η p 2 = 0.23, and no effect of group, F = 1.86, p = 0.19, despite a clear visual trend showing decreased freezing in middle-aged and old animals.

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a trend toward significancep = 0.06so close (0.05 < p ≤ 0.1)

Planned comparisons showed that groups did not differ during the CS period, p = 0.16, showed a trend toward significance in the ITI, p = 0.06, and differed significantly during the Post-CS period, p = 0.04.

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