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Tobacco, but Not Nicotine and Flavor-Less Electronic Cigarettes, Induces ACE2 and Immune Dysregulation.

Int J Mol Sci · 2020 · PMC7432384 · PMID 32752138

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highly significantno p-value reported
However, users of nicotine/flavor-containing e-cigs also exhibited highly significant upregulation of inflammasome-related genes, including NOD2, CCL5, and ASC (also known as PYCARD) ( Figure 3 ).

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