A TOMM40/APOE allele encoding APOE-E3 predicts high likelihood of late-onset Alzheimer's disease in autopsy cases.

Mol Genet Genomic Med · 2020 · PMC7434743 · PMID 32472747

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp = 3.2 × 10 −81actually significant

In late onset AD (LOAD), SNPs near APOE gave highly significant results (e.g., rs2075650, p = 3.2 × 10 −81 ), but no other genome‐wide significant evidence for association was found (Wijsman et al., 2011 ).

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