The combination of non-toxic concentration of LY and TAM showed highly significant synergistic interaction as observed from isobologram (IC 50 : 0.17 μM, combination index: 0.18, colony formation: 9.01%) compared to untreated control.
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Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells.
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