Neglected, Drug-Induced Platinum Accumulation Causes Immune Toxicity.

Front Pharmacol · 2020 · PMC7438596 · PMID 32903504

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a decreasing trendno p-value reported

A decreasing trend was observed from the fourth time point, which we suspect was due to greater clearance of the original drug because of the development of resistance to platinum drugs in patients.

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an increasing trendno p-value reported

In addition, there was an increasing trend over the first three time points, which reflected the platinum accumulation.

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