However, the conclusions are unchanged; either method of meta-analysis confirms highly significant differences in the mean retinal thickness of healthy controls and patients with MS.
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Focus on Data: Statistical Significance, Effect Size and the Accumulation of Evidence Achieved by Combining Study Results Through Meta-analysis.
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The major emphasis in this tutorial is on how to best combine the results of various studies, through a meta-analysis approach to determine if an overall effect is likely to be significant and consistent across similar studies, which helps to bolster the rigor and repeatability of conclusions.