28–30 Moreover, a statistically significant association was reported between a high fold change in CD8 from baseline to week 4 and PFS, and a positive trend in terms of overall survival was reported in patients with a high fold change in CD8 from baseline to week 6.
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Dose escalation phase 1 study of radiotherapy in combination with anti-cytotoxic-T-lymphocyte-associated antigen 4 monoclonal antibody ipilimumab in patients with metastatic melanoma.
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