Barely Significant
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Optimizing Predictive Performance of Bayesian Forecasting for Vancomycin Concentration in Intensive Care Patients.

Pharm Res · 2020 · PMC7443423 · PMID 32830297

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a decreasing trendno p-value reported
The random-effect of CL showed a decreasing trend over time while that of V was rather stable.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.