The AFSUMB Consensus Statements and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound using Sonazoid.

(B-1) (Agreement level 8.2, evidence level 7.7, recommendation level 8.5) In cirrhotic liver Background Risk factors for primary liver cancers such as HCC or ICC include hepatitis B or hepatitis C infection, cirrhosis, nonalcoholic steatohepatitis, and diabetes mellitus.[ 106 ] Annual incidence rates of HCC show an increasing trend in patients with developing cirrhosis.[ 107 ] Therefore, US surveillance of patients with chronic liver disease is essential (1) to improve early tumor detection and diagnosis of liver cancers and (2) to provide an opportunity for curative treatment.

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