Long-term opioid therapy for chronic noncancer pain: second update of the German guidelines.

Pain Rep · 2020 · PMC7447355 · PMID 32904018

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highly significantno p-value reported

We found one systematic review, which ranked pain relief, nausea, and vomiting as highly significant outcomes across studies.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.