Long-Term Safety and Effectiveness of the Xanthine Oxidoreductase Inhibitor, Topiroxostat in Japanese Hyperuricemic Patients with or Without Gout: A 54-week Open-label, Multicenter, Post-marketing Observational Study.

Clin Drug Investig · 2020 · PMC7452866 · PMID 32621143

Europe PMC DOI

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an increasing trendno p-value reported

Changes in Clinical Test Values Serum creatinine tended to increase after 10 weeks’ administration, and a significant difference was observed compared to the start of administration after 30 weeks’ administration, but the mean change after 54 weeks was a slight increase of 0.066, BUN did not show an increasing trend.

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