Gut microbiota is involved in the alleviation of loperamide-induced constipation by honey supplementation in mice.

Honey treatment leads to a decreasing trend in the contents of inhibitory neurotransmitter VIP and 5‐HT, and an increasing trend in the expression of excitatory neurotransmitter SP (all p > .05). 3.3 Honey re‐established the equilibrium of intestinal microecosystem The modulatory effect of honey on the intestinal microbiota was investigated by sequencing of the V3‐V4 region of the 16S rRNA gene of the predominant bacteria in mice.

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