Role of Adipose Tissue-Derived Autotaxin, Lysophosphatidate Signaling, and Inflammation in the Progression and Treatment of Breast Cancer.

Int J Mol Sci · 2020 · PMC7460696 · PMID 32824846

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Role of Adipose Tissue as a Source of ATX Production in Breast Cancer ATX is secreted directly in highly significant amounts by melanoma, glioblastoma, glioma, and thyroid tumors when compared to stomach, breast, lung, ovary, colorectal, and pancreatic tumors [ 61 , 62 , 63 , 64 ] ( Figure 2 A).

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