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Early biochemical effects of velmanase alfa in a 7-month-old infant with alpha-mannosidosis.

JIMD Rep · 2020 · PMC7463052 · PMID 32905047

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a decreasing trendno p-value reported
The reduction has been observed since the second week of ERT with a decreasing trend up to the end of the second month.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.