highly significantp < 0.0001
Moreover, the effect of anticoagulation became more pronounced when we analyzed single miRNA ∆Cq levels over time ( Figure 3 B), resulting in a highly significant ( p < 0.0001) difference between CTAD and EDTA plasma for the miRNAs miR-191-5p, miR-320a, miR-126-3p, and miR-21-5p.