Development of an Individualized Prediction Calculator for the Benefit of Postoperative Radiotherapy in Patients with Surgically Resected De Novo Stage IV Breast Cancer.

In particular, its retrospective nature means that it might be biased towards patients with a better prognosis for the use of PORT; however, all of the selected patients had good performance status so that they were candidates for upfront surgery despite the presence of metastasis, and PS matching was also conducted, thus the impact of selection bias might not be significant.

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