E-Cigarette Exposure Decreases Bone Marrow Hematopoietic Progenitor Cells.

Cancers (Basel) · 2020 · PMC7464997 · PMID 32824092

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.1400

boldest claim

The sentences

almost significantlyp = 0.058so close (0.05 < p ≤ 0.1)

After one month of E-cigarette exposure, the relative frequency of JAK2 V617F cells in the peripheral blood was almost significantly more than the air exposed group ( p = 0.058) ( Figure 6 B).

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failed to reach significancep = 0.14not close (p > 0.1)

In addition, there was a trend toward decreased long-term repopulating hematopoietic stem cells (LT-HSCs), defined as (LKS-SLAM; LKS-CD48 − CD150 + ), but failed to reach significance ( p = 0.14) ( Figure 3 C).

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highly significantno p-value reported

Given that we did not observe a highly significant decline in the LT-HSC population in the E-cigarette exposure group, it is most likely that the subtle difference was not sufficient to induce a difference in reconstitution capacity.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.