Oncologic Benefit of Adjuvant Chemoradiation after D2 Gastrectomy: A Stepwise Hierarchical Pooled Analysis and Systematic Review.

Cancers (Basel) · 2020 · PMC7465129 · PMID 32751879

Europe PMC DOI

hedged sentences

0.0550

closest p · 1.1× alpha

0.0660

boldest claim

The sentences

marginally significantp = 0.055so close (0.05 < p ≤ 0.1)

However, the difference was marginally significant in the subgroup analysis of balanced studies (OR: 1.279, p = 0.055) and significant in the subgroup analysis of studies involving stage ≥III patients only (OR: 1.663, p = 0.005).

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borderline significancep = 0.066so close (0.05 < p ≤ 0.1)

However, there was no statistically significant difference in the subgroup analysis of RCTs alone (OR: 0.788, 95% CI: 0.589–1.054, p = 0.108), whereas borderline significance was noted when analyzing balanced studies alone (OR: 0.802, 95% CI: 0.634–1.015, p = 0.066).

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