In advanced stages of CKD (eGFR <45 mL/min/1.73 m 2 ), this distinction failed to reach significance, likely due to the small number of patients included in this subgroup (based on the given results, a total of 238 patients, instead of the available 129, would have been needed to reach the significance level of 0.01 to distinguish ORN from non-obese nephropathy).
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The sentences
The highly significant inverse correlation between slopes of eGFR and BMI is shown in Figure 4 .