PD-1 checkpoint blockade in advanced melanoma patients: NK cells, monocytic subsets and host PD-L1 expression as predictive biomarker candidates.

In the model comparing baseline samples with PFS as a discriminatory variable, a separation between patients with short and long PFS ( Figure 1a ) with an overall fit (R 2 ) value of 73.5%, a predictive capacity (Q 2 ) of 54.9% and a highly significant cross-validated ANOVA P value (p[CV-ANOVA] = 0.0001) was observed.

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