Patterns of CAG repeat instability in the central nervous system and periphery in Huntington's disease and in spinocerebellar ataxia type 1.

Finally, we compared expansion indices between cerebellum and BA9, exhibiting low and high instability respectively, from eight additional HD individuals with repeat lengths from 40 to 48 CAGs and found a highly significant correlation ( R 2 = 0.93, P < 0.0001) between the two measures ( Fig. 6C ).

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