<i>Clostridioides difficile</i> infections in Saudi Arabia: Where are we standing?

One of these studies was able to detect an increasing trend of healthcare-associated CDIs from 17% in 2001 to 20% in 2018 out of all suspected diarrhea samples tested ( Al-Tawfiq et al., 2020 ). 1.1 Clostridioides difficile virulence strains The most hypervirulent strain detected during last decade was the North American pulsed-field gel electrophoresis type 1, restriction endonuclease analysis type B1, polymerase chain reaction ribotype 027, (NAP1/B1/027) and also referred to as ribotype 027 (RT027) which is also highly resistant to fluoroquinolones and metronidazole ( Fatima and Aziz, 2019 , Freeman et al., 2018 ).

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